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Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.
What can humans do? What can machines do? How do humans delegate actions to machines? In this book, Harry Collins and Martin Kusch combine insights from sociology and philosophy to provide a novel answer to these increasingly important questions.The authors begin by distinguishing between two basic types of intentional behavior, which they call polimorphic actions and mimeomorphic actions. Polimorphic actions (such as writing a love letter) are ones that community members expect to vary with social context. Mimeomorphic actions (such a swinging a golf club) do not vary. Although machines cannot act, they can mimic mimeomorphic actions. Mimeomorphic actions are thus the crucial link between what humans can do and what machines can do. Following a presentation of their detailed categorization of actions, the authors apply their approach to a broad range of human-machine interactions and to learning. Key examples include bicycle riding and the many varieties of writing machines. They also show how their theory can be used to explain the operation of organizations such as restaurants and armies. Finally, they look at a historical case—the technological development of the air pump—applying their categorization of actions to the processes of mechanization and automation. Automation, they argue, can occur only where what we want to bring about can be brought about through mimeomorphic action.
Defending Class Actions in Canada is aimed at businesses that may become defendants in class actions in Canada and the lawyers who defend them. Companies doing business in this country now have an intense interest in the proliferation of class actions and the risks posed by that development to their operations. This book not only outlines all of the steps in such actions and the law that governs them, it provides a useful analysis on a national scale of the most important developments and predictions of future trends.
This is the second volume of the new subseries "Invariant Theory and Algebraic Transformation Groups". The aim of the survey by A. Bialynicki-Birula is to present the main trends and achievements of research in the theory of quotients by actions of algebraic groups. This theory contains geometric invariant theory with various applications to problems of moduli theory. The contribution by J. Carrell treats the subject of torus actions on algebraic varieties, giving a detailed exposition of many of the cohomological results one obtains from having a torus action with fixed points. Many examples, such as toric varieties and flag varieties, are discussed in detail. W.M. McGovern studies the actions of a semisimple Lie or algebraic group on its Lie algebra via the adjoint action and on itself via conjugation. His contribution focuses primarily on nilpotent orbits that have found the widest application to representation theory in the last thirty-five years.
Complete with a state-by-state analysis of the ways in which the class action rules differ from the Federal Rule of Civil Procedure 23, this comprehensive guide provides practitioners with an understanding of the intricacies of a class action lawsuit. Multiple authors contributed to the book, mainly 12 top litigators at the premiere law firm of Fulbright and Jaworski, L.L.P.
Long regarded as a powerful means to seek individual damages against a corporate defendant, class actions have become a staple of the U.S. litigation system. In recent years, however, several highly significant Supreme Court decisions have weakened the commonality claims of defendants, particularly in workplace discrimination actions. In light of this background, the trends and prospects of employment class actions were the theme of the 56th annual proceedings of the prestigious New York University Conference on Labor, held in May 2003. This important volume reprints the papers presented at that conference, as well as some additional contributions. Among the considerable expertise brought to bear on this controversial subject, readers will find insightful analysis of such issues as the following: Effect of class actions on losing companies; Importance of class actions to Title VII enforcement; Obstacles to class litigation; Compliance and internal enforcement challenges for large employers; Opt-in vs. opt-out alternatives for class members; Value and effectiveness of pattern or practice test cases; Legal limits of group identity; Shifting of the burden of proof; Authority of arbitrators to proceed on a class wide basis; and Countering statistical claims of expert witnesses. Because class actions are based on tension - that between commonality and individuation - they tend to accumulate precedent along a spectrum from disconnected disparity to meaningful resolution. In this deeply informed and thought-provoking book, lawyers and academics concerned with both the interests of employers and of employees will proceed with increased awareness as they work on reconciling the practical and theoretical constraints of class litigation.
This volume contains the proceedings of a conference, sponsored by the Canadian Mathematical Society, on Group Actions and Invariant Theory, held in August, 1988 in Montreal. The conference was the third in a series bringing together researchers from North America and Europe (particularly Poland). The papers collected here will provide an overview of the state of the art of research in this area. The conference was primarily concerned with the geometric side of invariant theory, including explorations of the linearization problem for reductive group actions on affine spaces (with a counterexample given recently by J. Schwarz), spherical and complete symmetric varieties, reductive quotients, automorphisms of affine varieties, and homogeneous vector bundles.
A compelling case for the re-examination of interface design models is presented by this text's assertion that human behavior is not taken into account in the planning model generally favored by artificial intelligence.
More frequently than ever, private owners of contaminated sites have good economic reasons for cleaning up the sites, regardless of any concern on the part of a government agency. And, once having undertaken the costs of cleanup, they naturally seek reimbursement of cleanup costs from those who are responsible for the contamination. Private Cost Recovery Actions Under CERCLA examines the law and policy of private cost recovery actions under Superfund. Private Cost Recovery Actions Under CERCLA explores the relationship between CERCLA`s liability provision and the statute`s contribution provision, a relationship that has caused substantial difficulty for courts and practitioners. Moreover, it gives practical advice to the attorneys and courts that must deal with the complexities and high transaction costs of contribution litigation. Anyone involved in the morass of CERCLA contribution litigation will benefit from Professor John Hyson's measured analysis and coherent advice.