The Chemist 2
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1,2,3-Thiadiazoles are a group of heterocycles whose derivatives are important in industry, medicine, and agriculture. This volume provides a complete treatment of this group of heterocycles with an emphasis on syntheses, structural data, properties, reactions, and applications.
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.Comprehensive Medicinal Chemistry II will be available online in 2007 via the proven platform ScienceDirect providing the user with enhanced features such as cross-referencing and dynamic linking. * Comprehensively reviews - for the first time in one single work - the strategies, technologies, principles and applications of modern medicinal chemistry * Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets * Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Granville is in a mess once more. The streets are infested with Charge, a deadly synthetic drug concocted by an enigma known as The Chemist. Tommy finds himself in the midst of scandal yet again, as terrifying danger closes in on him; drugs, deaths and deception. After hitting a rocky patch with Kirsten and things at home as tricky as ever, Tommy feels as though he is invisible. But when Detective Brightwell calls upon his help in cracking the case, Tommy is immediately immersed into the Granville underworld, with the key surely lying with infamous crime family, the O'Clearys. With the threat of Smiler looming, trustworthy people are hard to find. So who can he count on this time to help him muddle through this impossible situation?The Rise of the Chemist is the second book in the Granville Series, sequel to The Disappearance of Timothy Dawson. It is a young adult fiction book, following Tommy's difficult battle for justice, in a town where crime rules. A series of teenage deaths triggered by a deadly synthetic drug, thrusts Tommy into the midst of an undercover operation. The targets? The Chemist, creator of the lethal, designer substance known as Charge, and the O'Clearys, a local crime family with their fingers in all kinds of illicit pies. With one eye looking over his shoulder for the threat of Smiler (book one), Tommy must decide between what is right and what is easy. With complications arising with Kirsten, and the relentless drive of Detective Brightwell, he finds himself questioning everybody and everything.Once injected into the O'Cleary family, Tommy comes face to face with a harsh, brutal reality, which he scrambles to escape from. But is it too late? Will Tommy find a way out? Will Granville ever be safe from Charge?Find out in The Rise of the Chemist.
British chemistry has traditionally been depicted as a solely male endeavour. However, this perspective is untrue: the allure of chemistry has attracted women since the earliest times. Despite the barriers placed in their path, women studied academic chemistry from the 1880s onwards and made interesting or significant contributions to their fields, yet they are virtually absent from historical records.Comprising a unique set of biographies of 141 of the 896 known women chemists from 1880 to 1949, this work attempts to address the imbalance by showcasing the determination of these women to survive and flourish in an environment dominated by men. Individual biographical accounts interspersed with contemporary quotes describe how women overcame the barriers of secondary and tertiary education, and of admission to professional societies. Although these women are lost to historical records, they are brought together here for the first time to show that a vibrant culture of female chemists did indeed exist in Britain during the late 19th and early 20th centuries.
The Chemistry of Chromium, Molybdenum and Tungsten deals with the chemistry of chromium, molybdenum, and tungsten. The discovery and history, occurrence and distribution, and production of all three elements are discussed, along with their industrial uses, preparation, and allotropes; nuclear, physical, and chemical properties; biological activities; and analytical chemistry. Organized into three sections, this volume begins with an overview of the history, occurrence and distribution, and production of chromium, molybdenum, and tungsten, as well as their industrial uses, preparation, and allotropes; nuclear, physical, and chemical properties; biological activities; and analytical chemistry. The intermetallic phases in binary alloys of all three elements are also considered, along with their oxidation states and respective compounds including compounds with non-metallic elements; compounds of ?-acceptor ligands; organometallic complexes; and peroxy compounds such as peroxychromates, tetraperoxy molybdates, and peroxy tungstates. This book will be of interest to inorganic chemists as well as students and researchers in the field of inorganic chemistry.
Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.